BDBM50319161 4-(N,N-bis-methylsulfonyl)-8-methoxy-3-methyl-1-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1083744

SMILES: CCCc1nc(C)c2c(nc3ccc(OC)nc3n12)N(S(C)(=O)=O)S(C)(=O)=O

InChI Key: InChIKey=BBXLNMHPPGLPDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50319161 (4-(N,N-bis-methylsulfonyl)-8-methoxy-3-methyl-1-pr...) Show SMILES CCCc1nc(C)c2c(nc3ccc(OC)nc3n12)N(S(C)(=O)=O)S(C)(=O)=O Show InChI InChI=1S/C16H21N5O5S2/c1-6-7-12-17-10(2)14-16(21(27(4,22)23)28(5,24)25)18-11-8-9-13(26-3)19-15(11)20(12)14/h8-9H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Biotie Therapies GmbH Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...				J Med Chem 53: 4399-411 (2010) Article DOI: 10.1021/jm1002793 BindingDB Entry DOI: 10.7270/Q2MK6D3N
					More data for this Ligand-Target Pair