BDBM50319220 6-[3-(3-amino-4-chloro-benzoyl)-ureido]-hexanoic acid hydroxyamide::CHEMBL1083100

SMILES: Nc1cc(ccc1Cl)C(=O)NC(=O)NCCCCCC(=O)NO

InChI Key: InChIKey=IZCWUTNWQCXAHC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50319220 (6-[3-(3-amino-4-chloro-benzoyl)-ureido]-hexanoic a...) Show SMILES Nc1cc(ccc1Cl)C(=O)NC(=O)NCCCCCC(=O)NO Show InChI InChI=1S/C14H19ClN4O4/c15-10-6-5-9(8-11(10)16)13(21)18-14(22)17-7-3-1-2-4-12(20)19-23/h5-6,8,23H,1-4,7,16H2,(H,19,20)(H2,17,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation				Bioorg Med Chem Lett 20: 3314-21 (2010) Article DOI: 10.1016/j.bmcl.2010.04.041 BindingDB Entry DOI: 10.7270/Q2GT5NCX
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50319220 (6-[3-(3-amino-4-chloro-benzoyl)-ureido]-hexanoic a...) Show SMILES Nc1cc(ccc1Cl)C(=O)NC(=O)NCCCCCC(=O)NO Show InChI InChI=1S/C14H19ClN4O4/c15-10-6-5-9(8-11(10)16)13(21)18-14(22)17-7-3-1-2-4-12(20)19-23/h5-6,8,23H,1-4,7,16H2,(H,19,20)(H2,17,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation				Bioorg Med Chem Lett 20: 3314-21 (2010) Article DOI: 10.1016/j.bmcl.2010.04.041 BindingDB Entry DOI: 10.7270/Q2GT5NCX
					More data for this Ligand-Target Pair