Found 6 hits for monomerid = 50319262 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50319262
(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)Show SMILES Cc1ccc(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 Show InChI InChI=1S/C26H30N2O5/c1-18-7-12-23(19(2)14-18)27-24(29)17-28(16-22-6-5-13-32-22)15-20-8-10-21(11-9-20)33-26(3,4)25(30)31/h5-14H,15-17H2,1-4H3,(H,27,29)(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma
Curated by ChEMBL
| Assay Description Agonist activity at Gal4-fused human PPARdelta |
Bioorg Med Chem Lett 20: 3376-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Mus musculus) | BDBM50319262
(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)Show SMILES Cc1ccc(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 Show InChI InChI=1S/C26H30N2O5/c1-18-7-12-23(19(2)14-18)27-24(29)17-28(16-22-6-5-13-32-22)15-20-8-10-21(11-9-20)33-26(3,4)25(30)31/h5-14H,15-17H2,1-4H3,(H,27,29)(H,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma
Curated by ChEMBL
| Assay Description Agonist activity at Gal4-fused mouse PPARalpha |
Bioorg Med Chem Lett 20: 3376-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50319262
(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)Show SMILES Cc1ccc(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 Show InChI InChI=1S/C26H30N2O5/c1-18-7-12-23(19(2)14-18)27-24(29)17-28(16-22-6-5-13-32-22)15-20-8-10-21(11-9-20)33-26(3,4)25(30)31/h5-14H,15-17H2,1-4H3,(H,27,29)(H,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma
Curated by ChEMBL
| Assay Description Agonist activity at Gal4-fused human PPARgamma |
Bioorg Med Chem Lett 20: 3376-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Mus musculus) | BDBM50319262
(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)Show SMILES Cc1ccc(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 Show InChI InChI=1S/C26H30N2O5/c1-18-7-12-23(19(2)14-18)27-24(29)17-28(16-22-6-5-13-32-22)15-20-8-10-21(11-9-20)33-26(3,4)25(30)31/h5-14H,15-17H2,1-4H3,(H,27,29)(H,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma
Curated by ChEMBL
| Assay Description Agonist activity at Gal4-fused mouse PPARdelta |
Bioorg Med Chem Lett 20: 3376-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50319262
(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)Show SMILES Cc1ccc(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 Show InChI InChI=1S/C26H30N2O5/c1-18-7-12-23(19(2)14-18)27-24(29)17-28(16-22-6-5-13-32-22)15-20-8-10-21(11-9-20)33-26(3,4)25(30)31/h5-14H,15-17H2,1-4H3,(H,27,29)(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma
Curated by ChEMBL
| Assay Description Agonist activity at Gal4-fused human PPARalpha |
Bioorg Med Chem Lett 20: 3376-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Mus musculus) | BDBM50319262
(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)Show SMILES Cc1ccc(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 Show InChI InChI=1S/C26H30N2O5/c1-18-7-12-23(19(2)14-18)27-24(29)17-28(16-22-6-5-13-32-22)15-20-8-10-21(11-9-20)33-26(3,4)25(30)31/h5-14H,15-17H2,1-4H3,(H,27,29)(H,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Bayer-Schering Pharma
Curated by ChEMBL
| Assay Description Agonist activity at Gal4-fused mouse PPARgamma |
Bioorg Med Chem Lett 20: 3376-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.019 BindingDB Entry DOI: 10.7270/Q27944V8 |
More data for this Ligand-Target Pair | |