BDBM50319360 1-(3-methoxyphenyl)-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one::CHEMBL1083125

SMILES: COc1cccc(c1)C(=O)CCc1cnnn1-c1ccccc1

InChI Key: InChIKey=VKEUKZZJQSNGRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319360 (1-(3-methoxyphenyl)-3-(1-phenyl-1H-tetrazol-5-yl)p...) Show SMILES COc1cccc(c1)C(=O)CCc1cnnn1-c1ccccc1 Show InChI InChI=1S/C18H17N3O2/c1-23-17-9-5-6-14(12-17)18(22)11-10-16-13-19-20-21(16)15-7-3-2-4-8-15/h2-9,12-13H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	215	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 3265-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ
					More data for this Ligand-Target Pair