BDBM50319436 (R)-4-((3-(1'-(4,6-dimethylpyrimidine-5-carbonyl)-4'-methyl-1,4'-bipiperidin-4-yl)-2-oxo-4-phenylimidazolidin-1-yl)methyl)-N-methylpiperidine-1-carboxamide::CHEMBL1085221

SMILES: CNC(=O)N1CCC(CN2C[C@H](N(C3CCN(CC3)C3(C)CCN(CC3)C(=O)c3c(C)ncnc3C)C2=O)c2ccccc2)CC1

InChI Key: InChIKey=PEYUSKSYYONOAP-PMERELPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50319436 ((R)-4-((3-(1'-(4,6-dimethylpyrimidine-5-carbonyl)-...) Show SMILES CNC(=O)N1CCC(CN2C[C@H](N(C3CCN(CC3)C3(C)CCN(CC3)C(=O)c3c(C)ncnc3C)C2=O)c2ccccc2)CC1 |r| Show InChI InChI=1S/C35H50N8O3/c1-25-31(26(2)38-24-37-25)32(44)39-20-14-35(3,15-21-39)42-18-12-29(13-19-42)43-30(28-8-6-5-7-9-28)23-41(34(43)46)22-27-10-16-40(17-11-27)33(45)36-4/h5-9,24,27,29-30H,10-23H2,1-4H3,(H,36,45)/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC Curated by ChEMBL					Assay Description Binding affinity at CCR5 receptor by radiolabelled RANTES binding assay				Bioorg Med Chem Lett 20: 3219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.04.077 BindingDB Entry DOI: 10.7270/Q2FT8M63
					More data for this Ligand-Target Pair