BDBM50319475 CHEMBL1082848::rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-2,5-dimethyl-indol-1-yl]-acetic acid

SMILES: Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(C)ccc2n1CC(O)=O

InChI Key: InChIKey=RRSJWWGATDVVSQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50319475 (CHEMBL1082848 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...) Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C19H18N2O4S/c1-11-7-8-15-14(9-11)18(12(2)21(15)10-17(22)23)19-13-5-3-4-6-16(13)26(24,25)20-19/h3-9,19-20H,10H2,1-2H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay				Bioorg Med Chem Lett 20: 3287-90 (2010) Article DOI: 10.1016/j.bmcl.2010.04.046 BindingDB Entry DOI: 10.7270/Q26973QW
					More data for this Ligand-Target Pair