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BDBM50319485 CHEMBL1085645::rac-[3-(1,1-Dioxo-2-phenyl-2,3-dihydro-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acid

SMILES: Cc1c(C2N(c3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O

InChI Key: InChIKey=JAXQBYVUYXMAES-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319485   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50319485
PNG
(CHEMBL1085645 | rac-[3-(1,1-Dioxo-2-phenyl-2,3-dih...)
Show SMILES Cc1c(C2N(c3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O
Show InChI InChI=1S/C24H20N2O4S/c1-16-23(18-11-5-7-13-20(18)25(16)15-22(27)28)24-19-12-6-8-14-21(19)31(29,30)26(24)17-9-3-2-4-10-17/h2-14,24H,15H2,1H3,(H,27,28)
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Article
PubMed
480n/an/an/an/an/an/an/an/a



Athersys, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay


Bioorg Med Chem Lett 20: 3287-90 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW
More data for this
Ligand-Target Pair