BDBM50319657 2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)propanamide::CHEMBL1084381

SMILES: CC(NCc1ccccc1)C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl

InChI Key: InChIKey=QICFULGAOAYEPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319657 (2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...) Show SMILES CC(NCc1ccccc1)C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl Show InChI InChI=1S/C19H18ClN3O2/c1-12(22-11-13-5-3-2-4-6-13)18(24)23-17-9-14-7-8-21-19(25)15(14)10-16(17)20/h2-10,12,22H,11H2,1H3,(H,21,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 3235-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.070 BindingDB Entry DOI: 10.7270/Q21N819Z
					More data for this Ligand-Target Pair