BDBM50319671 1-(4-Piperidin-1-yl)butyl-3-(4-pyridin-3-ylphenyl)urea::CHEMBL1086089

SMILES: O=C(NCCCCN1CCCCC1)Nc1ccc(cc1)-c1cccnc1

InChI Key: InChIKey=VQCSQLSSMLSFLL-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50319671 (1-(4-Piperidin-1-yl)butyl-3-(4-pyridin-3-ylphenyl)...) Show SMILES O=C(NCCCCN1CCCCC1)Nc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C21H28N4O/c26-21(23-13-2-5-16-25-14-3-1-4-15-25)24-20-10-8-18(9-11-20)19-7-6-12-22-17-19/h6-12,17H,1-5,13-16H2,(H2,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human))	BDBM50319671 (1-(4-Piperidin-1-yl)butyl-3-(4-pyridin-3-ylphenyl)...) Show SMILES O=C(NCCCCN1CCCCC1)Nc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C21H28N4O/c26-21(23-13-2-5-16-25-14-3-1-4-15-25)24-20-10-8-18(9-11-20)19-7-6-12-22-17-19/h6-12,17H,1-5,13-16H2,(H2,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Targacept, Inc Curated by ChEMBL					Assay Description Agonist activity at alpha7 nAChR				J Med Chem 54: 7943-61 (2011) Article DOI: 10.1021/jm2007672 BindingDB Entry DOI: 10.7270/Q29P32QP
					More data for this Ligand-Target Pair