BDBM50319682 1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin-1-yl)butyl)urea::CHEMBL1083485

SMILES: Fc1ccccc1-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1

InChI Key: InChIKey=YOCUJVXRRWEPDN-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50319682 (1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 Show InChI InChI=1S/C21H27FN4O/c22-19-9-3-2-8-18(19)20-11-10-17(16-24-20)25-21(27)23-12-4-7-15-26-13-5-1-6-14-26/h2-3,8-11,16H,1,4-7,12-15H2,(H2,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assay				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50319682 (1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 Show InChI InChI=1S/C21H27FN4O/c22-19-9-3-2-8-18(19)20-11-10-17(16-24-20)25-21(27)23-12-4-7-15-26-13-5-1-6-14-26/h2-3,8-11,16H,1,4-7,12-15H2,(H2,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair