BDBM50319694 (+/-)-2-Amino-(bis-2-chloroethyl)-5-aminoindane-2-carboxylic acid::CHEMBL1084594

SMILES: NC1(Cc2ccc(cc2C1)N(CCCl)CCCl)C(O)=O

InChI Key: InChIKey=YOYUWLUUYLEOJW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Large neutral amino acids transporter small subunit 1 (Rattus norvegicus)	BDBM50319694 ((+/-)-2-Amino-(bis-2-chloroethyl)-5-aminoindane-2-...) Show SMILES NC1(Cc2ccc(cc2C1)N(CCCl)CCCl)C(O)=O Show InChI InChI=1S/C14H18Cl2N2O2/c15-3-5-18(6-4-16)12-2-1-10-8-14(17,13(19)20)9-11(10)7-12/h1-2,7H,3-6,8-9,17H2,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of LAT1-mediated L-[14C]-leucine uptake in Sprague-Dawley rat brain by duel-labeled liquid scintillation counting				Bioorg Med Chem Lett 20: 3688-91 (2010) Article DOI: 10.1016/j.bmcl.2010.04.086 BindingDB Entry DOI: 10.7270/Q2HM58MR
					More data for this Ligand-Target Pair