BDBM50319915 4-morpholino-7-(thiophen-2-yl)-2H-chromen-2-one::CHEMBL1085747

SMILES: O=c1cc(N2CCOCC2)c2ccc(cc2o1)-c1cccs1

InChI Key: InChIKey=WPOISDXDFNAMSY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50319915 (4-morpholino-7-(thiophen-2-yl)-2H-chromen-2-one | ...) Show SMILES O=c1cc(N2CCOCC2)c2ccc(cc2o1)-c1cccs1 Show InChI InChI=1S/C17H15NO3S/c19-17-11-14(18-5-7-20-8-6-18)13-4-3-12(10-15(13)21-17)16-2-1-9-22-16/h1-4,9-11H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Hradec Kralove Curated by ChEMBL					Assay Description Inhibition of DNA-PK (unknown origin)				J Med Chem 58: 41-71 (2015) Article DOI: 10.1021/jm501026z BindingDB Entry DOI: 10.7270/Q2P84DJ7
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50319915 (4-morpholino-7-(thiophen-2-yl)-2H-chromen-2-one | ...) Show SMILES O=c1cc(N2CCOCC2)c2ccc(cc2o1)-c1cccs1 Show InChI InChI=1S/C17H15NO3S/c19-17-11-14(18-5-7-20-8-6-18)13-4-3-12(10-15(13)21-17)16-2-1-9-22-16/h1-4,9-11H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of DNA-dependent protein kinase				Bioorg Med Chem Lett 20: 3649-53 (2010) Article DOI: 10.1016/j.bmcl.2010.04.102 BindingDB Entry DOI: 10.7270/Q2R49QX1
					More data for this Ligand-Target Pair