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SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(C=C)c1ccccc1

InChI Key: InChIKey=OAIQMVJUJXKRRX-IKOFQBKESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319999   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50319999
PNG
((2R)-1-(2-methyl-1-(naphthalen-2-yl)propan-2-ylami...)
Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(C=C)c1ccccc1 |r|
Show InChI InChI=1S/C26H31NO2/c1-4-25(22-11-6-5-7-12-22)29-19-24(28)18-27-26(2,3)17-20-14-15-21-10-8-9-13-23(21)16-20/h4-16,24-25,27-28H,1,17-19H2,2-3H3/t24-,25?/m1/s1
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PubMed
n/an/a 210n/an/an/an/an/an/a



Central Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay

Bioorg Med Chem Lett 20: 3809-13 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.035
BindingDB Entry DOI: 10.7270/Q2765FGD
More data for this
Ligand-Target Pair