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SMILES: CCCCC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1

InChI Key: InChIKey=NLMPOLGGLBGXKT-AVJYQCBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320002   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50320002
PNG
((2R)-1-(2-methyl-1-(naphthalen-2-yl)propan-2-ylami...)
Show SMILES CCCCC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 |r|
Show InChI InChI=1S/C28H37NO2/c1-4-5-15-27(24-12-7-6-8-13-24)31-21-26(30)20-29-28(2,3)19-22-16-17-23-11-9-10-14-25(23)18-22/h6-14,16-18,26-27,29-30H,4-5,15,19-21H2,1-3H3/t26-,27?/m1/s1
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PubMed
n/an/a 170n/an/an/an/an/an/a



Central Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay

Bioorg Med Chem Lett 20: 3809-13 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.035
BindingDB Entry DOI: 10.7270/Q2765FGD
More data for this
Ligand-Target Pair