Found 3 hits for monomerid = 50320124 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50320124
(3-(2-((2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl)-2-o...)Show SMILES COc1ccc(NC(=O)CC(C)(C)NCC(=O)N2C[C@@H](F)C[C@H]2C#N)nc1 |r| Show InChI InChI=1S/C18H24FN5O3/c1-18(2,7-16(25)23-15-5-4-14(27-3)9-21-15)22-10-17(26)24-11-12(19)6-13(24)8-20/h4-5,9,12-13,22H,6-7,10-11H2,1-3H3,(H,21,23,25)/t12-,13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 20: 3596-600 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.124 BindingDB Entry DOI: 10.7270/Q29Z953W |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50320124
(3-(2-((2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl)-2-o...)Show SMILES COc1ccc(NC(=O)CC(C)(C)NCC(=O)N2C[C@@H](F)C[C@H]2C#N)nc1 |r| Show InChI InChI=1S/C18H24FN5O3/c1-18(2,7-16(25)23-15-5-4-14(27-3)9-21-15)22-10-17(26)24-11-12(19)6-13(24)8-20/h4-5,9,12-13,22H,6-7,10-11H2,1-3H3,(H,21,23,25)/t12-,13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes
Curated by ChEMBL
| Assay Description Inhibition of DPP4 in presence of 50% human serum |
Bioorg Med Chem Lett 20: 3596-600 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.124 BindingDB Entry DOI: 10.7270/Q29Z953W |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase VIII
(Homo sapiens (Human)) | BDBM50320124
(3-(2-((2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl)-2-o...)Show SMILES COc1ccc(NC(=O)CC(C)(C)NCC(=O)N2C[C@@H](F)C[C@H]2C#N)nc1 |r| Show InChI InChI=1S/C18H24FN5O3/c1-18(2,7-16(25)23-15-5-4-14(27-3)9-21-15)22-10-17(26)24-11-12(19)6-13(24)8-20/h4-5,9,12-13,22H,6-7,10-11H2,1-3H3,(H,21,23,25)/t12-,13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes
Curated by ChEMBL
| Assay Description Inhibition of DPP8 |
Bioorg Med Chem Lett 20: 3596-600 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.124 BindingDB Entry DOI: 10.7270/Q29Z953W |
More data for this Ligand-Target Pair | |