BDBM50320285 (3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-N,N-dimethylhexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide::CHEMBL1085269
SMILES: CN(C)C(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)NCC(=O)N1CCC[C@H]1C#N
InChI Key: InChIKey=BRAWVUJRLDASDM-XGUBFFRZSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50320285 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of DPP4 | Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM50320285 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of DPP9 | Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase VIII (Homo sapiens (Human)) | BDBM50320285 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of DPP8 | Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ | |||||||||||
More data for this Ligand-Target Pair |