BDBM50320519 4,4'-thiodipyridine-3-sulfonamide::CHEMBL1164504

SMILES: NS(=O)(=O)c1cnccc1Sc1ccncc1S(N)(=O)=O

InChI Key: InChIKey=JYMNSJBFCKCLMB-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50320519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50320519 (4,4'-thiodipyridine-3-sulfonamide | CHEMBL1164504) Show SMILES NS(=O)(=O)c1cnccc1Sc1ccncc1S(N)(=O)=O Show InChI InChI=1S/C10H10N4O4S3/c11-20(15,16)9-5-13-3-1-7(9)19-8-2-4-14-6-10(8)21(12,17)18/h1-6H,(H2,11,15,16)(H2,12,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50320519 (4,4'-thiodipyridine-3-sulfonamide | CHEMBL1164504) Show SMILES NS(=O)(=O)c1cnccc1Sc1ccncc1S(N)(=O)=O Show InChI InChI=1S/C10H10N4O4S3/c11-20(15,16)9-5-13-3-1-7(9)19-8-2-4-14-6-10(8)21(12,17)18/h1-6H,(H2,11,15,16)(H2,12,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50320519 (4,4'-thiodipyridine-3-sulfonamide | CHEMBL1164504) Show SMILES NS(=O)(=O)c1cnccc1Sc1ccncc1S(N)(=O)=O Show InChI InChI=1S/C10H10N4O4S3/c11-20(15,16)9-5-13-3-1-7(9)19-8-2-4-14-6-10(8)21(12,17)18/h1-6H,(H2,11,15,16)(H2,12,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Homo sapiens (Human))	BDBM50320519 (4,4'-thiodipyridine-3-sulfonamide | CHEMBL1164504) Show SMILES NS(=O)(=O)c1cnccc1Sc1ccncc1S(N)(=O)=O Show InChI InChI=1S/C10H10N4O4S3/c11-20(15,16)9-5-13-3-1-7(9)19-8-2-4-14-6-10(8)21(12,17)18/h1-6H,(H2,11,15,16)(H2,12,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human full length carbonic anhydrase 14 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50320519 (4,4'-thiodipyridine-3-sulfonamide | CHEMBL1164504) Show SMILES NS(=O)(=O)c1cnccc1Sc1ccncc1S(N)(=O)=O Show InChI InChI=1S/C10H10N4O4S3/c11-20(15,16)9-5-13-3-1-7(9)19-8-2-4-14-6-10(8)21(12,17)18/h1-6H,(H2,11,15,16)(H2,12,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair