BDBM50320884 3-(3-Chloro-benzyl)-5-(4-methanesulfonyl-benzylidene)-thiazolidine-2,4-dione::CHEMBL1164770

SMILES: CS(=O)(=O)c1ccc(\C=C2/SC(=O)N(Cc3cccc(Cl)c3)C2=O)cc1

InChI Key: InChIKey=JYUNPCQNWMVFGH-YBEGLDIGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50320884 (3-(3-Chloro-benzyl)-5-(4-methanesulfonyl-benzylide...) Show SMILES CS(=O)(=O)c1ccc(\C=C2/SC(=O)N(Cc3cccc(Cl)c3)C2=O)cc1 Show InChI InChI=1S/C18H14ClNO4S2/c1-26(23,24)15-7-5-12(6-8-15)10-16-17(21)20(18(22)25-16)11-13-3-2-4-14(19)9-13/h2-10H,11H2,1H3/b16-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Pernambuco Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPARgamma ligand binding domain expressed in Escherichia coli BL21 after 12 hrs by liquid scintillation ...				Bioorg Med Chem 18: 3805-11 (2010) Article DOI: 10.1016/j.bmc.2010.04.045 BindingDB Entry DOI: 10.7270/Q28S4Q24
					More data for this Ligand-Target Pair