BDBM50320974 2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylicacid(5-methyl-isoxazol-4-ylmethyl)-amide::CHEMBL1164358

SMILES: Cc1oncc1CNC(=O)c1ccc2cc([nH]c2c1)-c1cc([nH]n1)-c1ccccc1

InChI Key: InChIKey=PORGQOZMAGWCOU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50320974 (2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...) Show SMILES Cc1oncc1CNC(=O)c1ccc2cc([nH]c2c1)-c1cc([nH]n1)-c1ccccc1 Show InChI InChI=1S/C23H19N5O2/c1-14-18(13-25-30-14)12-24-23(29)17-8-7-16-9-21(26-19(16)10-17)22-11-20(27-28-22)15-5-3-2-4-6-15/h2-11,13,26H,12H2,1H3,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed Pharma Pvt. Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assay				Bioorg Med Chem 18: 4547-59 (2010) Article DOI: 10.1016/j.bmc.2010.04.056 BindingDB Entry DOI: 10.7270/Q2N29X4K
					More data for this Ligand-Target Pair