BDBM50321223 (+/-)-6-Chloro-1-(indol-3-yl)-2-isobutyryl-1,2,3,4-tetrahydro-beta-carboline::CHEMBL1163729

SMILES: CCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12

InChI Key: InChIKey=AYAWZIKJMLSOJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50321223 ((+/-)-6-Chloro-1-(indol-3-yl)-2-isobutyryl-1,2,3,4...) Show SMILES CCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H22ClN3O/c1-2-5-21(28)27-11-10-16-17-12-14(24)8-9-20(17)26-22(16)23(27)18-13-25-19-7-4-3-6-15(18)19/h3-4,6-9,12-13,23,25-26H,2,5,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair