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SMILES: CCOC(=O)C1Cc2c([nH]c3ccccc23)C(N1C(=O)C(C)C)c1cccc(O)c1

InChI Key: InChIKey=NWQGWFQMZIAQGH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321247   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50321247
PNG
((+/-)-Ethyl 1-(3-hydroxyphenyl)-2-isobutyryl-1,2,3...)
Show SMILES CCOC(=O)C1Cc2c([nH]c3ccccc23)C(N1C(=O)C(C)C)c1cccc(O)c1
Show InChI InChI=1S/C24H26N2O4/c1-4-30-24(29)20-13-18-17-10-5-6-11-19(17)25-21(18)22(26(20)23(28)14(2)3)15-8-7-9-16(27)12-15/h5-12,14,20,22,25,27H,4,13H2,1-3H3
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MMDB

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n/an/a 380n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry

Bioorg Med Chem 18: 4167-77 (2010)


Article DOI: 10.1016/j.bmc.2010.05.024
BindingDB Entry DOI: 10.7270/Q2BK1CJP
More data for this
Ligand-Target Pair