BDBM50321371 4-Cyano-1H-imidazole-2-carboxylicacid[2-cyclohex-1-enyl-4-(2,6-dimethyl-1,1-dioxo-1lambda*6*-[1,2,6]thiadiazinan-4-yl)-phenyl]-amide::CHEMBL1171607

SMILES: CN1CC(CN(C)S1(=O)=O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1

InChI Key: InChIKey=UBCZMKNXPWCKQP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50321371 (4-Cyano-1H-imidazole-2-carboxylicacid[2-cyclohex-1...) Show SMILES CN1CC(CN(C)S1(=O)=O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1 |t:29| Show InChI InChI=1S/C22H26N6O3S/c1-27-13-17(14-28(2)32(27,30)31)16-8-9-20(19(10-16)15-6-4-3-5-7-15)26-22(29)21-24-12-18(11-23)25-21/h6,8-10,12,17H,3-5,7,13-14H2,1-2H3,(H,24,25)(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human FMS by fluorescence polarization				Bioorg Med Chem Lett 20: 3925-9 (2010) Article DOI: 10.1016/j.bmcl.2010.05.013 BindingDB Entry DOI: 10.7270/Q22Z16HG
					More data for this Ligand-Target Pair