BDBM50321420 3-(benzo[d]oxazol-2-yl)-5-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine tetrahydrochloride::CHEMBL1170607

SMILES: Nc1ncc(cc1-c1nc2ccccc2o1)-c1cnn(c1)C1CCOCC1

InChI Key: InChIKey=DFWNKJQCTALOPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50321420 (3-(benzo[d]oxazol-2-yl)-5-(1-(tetrahydro-2H-pyran-...) Show SMILES Nc1ncc(cc1-c1nc2ccccc2o1)-c1cnn(c1)C1CCOCC1 Show InChI InChI=1S/C20H19N5O2/c21-19-16(20-24-17-3-1-2-4-18(17)27-20)9-13(10-22-19)14-11-23-25(12-14)15-5-7-26-8-6-15/h1-4,9-12,15H,5-8H2,(H2,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-MET by HTRF assay				Bioorg Med Chem Lett 20: 4223-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.031 BindingDB Entry DOI: 10.7270/Q2JW8FTQ
					More data for this Ligand-Target Pair