BDBM50321429 (4-(4-(6-amino-5-(benzo[d]oxazol-2-yl)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)(phenyl)methanone tetrahydrochloride::CHEMBL1171025

SMILES: Nc1ncc(cc1-c1nc2ccccc2o1)-c1cnn(c1)C1CCN(CC1)C(=O)c1ccccc1

InChI Key: InChIKey=HGMVZBFXUFZMFS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50321429 ((4-(4-(6-amino-5-(benzo[d]oxazol-2-yl)pyridin-3-yl...) Show SMILES Nc1ncc(cc1-c1nc2ccccc2o1)-c1cnn(c1)C1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C27H24N6O2/c28-25-22(26-31-23-8-4-5-9-24(23)35-26)14-19(15-29-25)20-16-30-33(17-20)21-10-12-32(13-11-21)27(34)18-6-2-1-3-7-18/h1-9,14-17,21H,10-13H2,(H2,28,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-MET by HTRF assay				Bioorg Med Chem Lett 20: 4223-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.031 BindingDB Entry DOI: 10.7270/Q2JW8FTQ
					More data for this Ligand-Target Pair