BDBM50321483 (6-(4-fluorophenoxy)pyridin-3-yl)(4-isopropylpiperazin-1-yl)methanone::CHEMBL1172337

SMILES: CC(C)N1CCN(CC1)C(=O)c1ccc(Oc2ccc(F)cc2)nc1

InChI Key: InChIKey=SFWADPRZACXNIG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321483 ((6-(4-fluorophenoxy)pyridin-3-yl)(4-isopropylpiper...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(Oc2ccc(F)cc2)nc1 Show InChI InChI=1S/C19H22FN3O2/c1-14(2)22-9-11-23(12-10-22)19(24)15-3-8-18(21-13-15)25-17-6-4-16(20)5-7-17/h3-8,13-14H,9-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...				Bioorg Med Chem Lett 20: 4210-4 (2010) Article DOI: 10.1016/j.bmcl.2010.05.041 BindingDB Entry DOI: 10.7270/Q29G5NS9
					More data for this Ligand-Target Pair