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SMILES: Clc1ccc(Oc2cccc(n2)C(=O)N2CCCN(CC2)C2CCC2)cc1Cl

InChI Key: InChIKey=BKTPKBQWTMYGGR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321492   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50321492
PNG
((4-cyclobutyl-1,4-diazepan-1-yl)(6-(3,4-dichloroph...)
Show SMILES Clc1ccc(Oc2cccc(n2)C(=O)N2CCCN(CC2)C2CCC2)cc1Cl
Show InChI InChI=1S/C21H23Cl2N3O2/c22-17-9-8-16(14-18(17)23)28-20-7-2-6-19(24-20)21(27)26-11-3-10-25(12-13-26)15-4-1-5-15/h2,6-9,14-15H,1,3-5,10-13H2
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Article
PubMed
 160n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development L.L.C.

Curated by ChEMBL


Assay Description
Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...

Bioorg Med Chem Lett 20: 4210-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.041
BindingDB Entry DOI: 10.7270/Q29G5NS9
More data for this
Ligand-Target Pair