BDBM50321824 4-((1H-Imidazol-4-yl)methyl)-1-(4-isopropylphenyl)piperidine::CHEMBL1172712

SMILES: CC(C)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=RZCPYANRTWAKSO-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321824 (4-((1H-Imidazol-4-yl)methyl)-1-(4-isopropylphenyl)...) Show SMILES CC(C)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H25N3/c1-14(2)16-3-5-18(6-4-16)21-9-7-15(8-10-21)11-17-12-19-13-20-17/h3-6,12-15H,7-11H2,1-2H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50321824 (4-((1H-Imidazol-4-yl)methyl)-1-(4-isopropylphenyl)...) Show SMILES CC(C)c1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H25N3/c1-14(2)16-3-5-18(6-4-16)21-9-7-15(8-10-21)11-17-12-19-13-20-17/h3-6,12-15H,7-11H2,1-2H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...				Bioorg Med Chem 18: 5441-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.052 BindingDB Entry DOI: 10.7270/Q2C82B88
					More data for this Ligand-Target Pair