BDBM50322041 CHEMBL1172935::Isopropyl(2S,6S)-4-{[(6,7-dimethyl-8H-indeno[1,2-d][1,3]thiazol-4-yl)oxy]methyl}-2,6,9-trimethyl-7-oxo-8-oxa-3,5-diaza-4-phosphadecan-1-oate4-oxide

SMILES: CC(C)OC(=O)[C@H](C)NP(=O)(COc1cc(C)c(C)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OC(C)C

InChI Key: InChIKey=YITPOKWZAXOVOD-ROUUACIJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50322041 (CHEMBL1172935 | Isopropyl(2S,6S)-4-{[(6,7-dimethyl...) Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(COc1cc(C)c(C)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OC(C)C |r| Show InChI InChI=1S/C25H36N3O6PS/c1-13(2)33-24(29)17(7)27-35(31,28-18(8)25(30)34-14(3)4)12-32-20-9-15(5)16(6)19-10-21-23(22(19)20)26-11-36-21/h9,11,13-14,17-18H,10,12H2,1-8H3,(H2,27,28,31)/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair