null

SMILES: CN(Cc1cccnc1)c1nc2c(nnn2c2ccsc12)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=ITMNONAOENDKLR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322095 (CHEMBL1173136 | N-methyl-3-(phenylsulfonyl)-N-(pyr...) Show SMILES CN(Cc1cccnc1)c1nc2c(nnn2c2ccsc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H16N6O2S2/c1-25(13-14-6-5-10-21-12-14)18-17-16(9-11-29-17)26-19(22-18)20(23-24-26)30(27,28)15-7-3-2-4-8-15/h2-12H,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322095 (CHEMBL1173136 | N-methyl-3-(phenylsulfonyl)-N-(pyr...) Show SMILES CN(Cc1cccnc1)c1nc2c(nnn2c2ccsc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H16N6O2S2/c1-25(13-14-6-5-10-21-12-14)18-17-16(9-11-29-17)26-19(22-18)20(23-24-26)30(27,28)15-7-3-2-4-8-15/h2-12H,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair