BDBM50322370 4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-yl)quinoline::CHEMBL1173017

SMILES: C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1

InChI Key: InChIKey=AEQHEVDDTLOOMD-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50322370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50322370 (4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-...) Show SMILES C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Siena Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometry				J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50322370 (4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-...) Show SMILES C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Siena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry				J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50322370 (4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-...) Show SMILES C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Siena Curated by ChEMBL					Assay Description Displacement of [3H]8OH-DPAT from 5HT1A receptor in rat CRL:CD(SD)BR-COBS hippocampus by scintillation spectrometry				J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50322370 (4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-...) Show SMILES C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Siena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry				J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50322370 (4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-...) Show SMILES C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Siena Curated by ChEMBL					Assay Description Binding affinity to human ERG expressed in HEK293 cells				J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP
					More data for this Ligand-Target Pair