BDBM50322634 (S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-2-amino-3-phenylpropanamido)-3-(naphthalen-1-yl)propanoyl)pyrrolidine-2-carboxamido)-4-methylpentanamido)propanamido)-5-guanidinopentanoic acid::CHEMBL1170220
SMILES: [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-c1cccc2ccccc12)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O
InChI Key: InChIKey=KXRIOYLSJCAEGF-LEOAUMQFSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human)) | BDBM50322634 ((S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-2-amino-3-p...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 720 | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at human C3a receptor in human U937 cells assessed as inhibition of intracellular calcium mobilization | J Med Chem 53: 4938-48 (2010) Article DOI: 10.1021/jm1003705 BindingDB Entry DOI: 10.7270/Q2QR4X9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human)) | BDBM50322634 ((S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-2-amino-3-p...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 720 | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Agonist activity at human C3a receptor in human U937 cells assessed as induction of intracellular calcium release | J Med Chem 53: 4938-48 (2010) Article DOI: 10.1021/jm1003705 BindingDB Entry DOI: 10.7270/Q2QR4X9F | |||||||||||
More data for this Ligand-Target Pair |