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SMILES: CNc1nc(SC)nc(SCc2ccccc2)c1C(O)=O

InChI Key: InChIKey=ZVLJEBDYJCTFKD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322689   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50322689
PNG
(4-(Benzylthio)-6-(methylamino)-2-(methylthio)pyrim...)
Show SMILES CNc1nc(SC)nc(SCc2ccccc2)c1C(O)=O
Show InChI InChI=1S/C14H15N3O2S2/c1-15-11-10(13(18)19)12(17-14(16-11)20-2)21-8-9-6-4-3-5-7-9/h3-7H,8H2,1-2H3,(H,18,19)(H,15,16,17)
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Similars
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Kyorin Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Partial agonist activity at human PPARgamma-LBD expressed in CHO-K1 cells co-transfected with GAL4 assessed as luciferase activity by transactivation...

J Med Chem 53: 5012-24 (2010)


Article DOI: 10.1021/jm100443s
BindingDB Entry DOI: 10.7270/Q24J0G3H
More data for this
Ligand-Target Pair