BDBM50322705 3-benzyl-5-((1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methylene)thiazolidine-2,4-dione::CHEMBL1173301

SMILES: Cn1c2ccc(\C=C3/SC(=O)N(Cc4ccccc4)C3=O)cc2n(C)c1=O

InChI Key: InChIKey=DGWRCFRFNQNCMG-BOPFTXTBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50322705 (3-benzyl-5-((1,3-dimethyl-2-oxo-2,3-dihydro-1H-ben...) Show SMILES Cn1c2ccc(\C=C3/SC(=O)N(Cc4ccccc4)C3=O)cc2n(C)c1=O Show InChI InChI=1S/C20H17N3O3S/c1-21-15-9-8-14(10-16(15)22(2)19(21)25)11-17-18(24)23(20(26)27-17)12-13-6-4-3-5-7-13/h3-11H,12H2,1-2H3/b17-11-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrate				J Med Chem 53: 4958-67 (2010) Article DOI: 10.1021/jm1005012 BindingDB Entry DOI: 10.7270/Q2G73DXK
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