BDBM50322835 CHEMBL1210243::N-((1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-N-(2-methyl-4-morpholinobutan-2-yl)cyclohexanecarboxamide

SMILES: Cn1c2ccccc2cc(CN(C(=O)C2CCCCC2)C(C)(C)CCN2CCOCC2)c1=O

InChI Key: InChIKey=KPFXQSSJRGMPNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide S receptor (Homo sapiens (Human))	BDBM50322835 (CHEMBL1210243 | N-((1-methyl-2-oxo-1,2-dihydroquin...) Show SMILES Cn1c2ccccc2cc(CN(C(=O)C2CCCCC2)C(C)(C)CCN2CCOCC2)c1=O Show InChI InChI=1S/C27H39N3O3/c1-27(2,13-14-29-15-17-33-18-16-29)30(26(32)21-9-5-4-6-10-21)20-23-19-22-11-7-8-12-24(22)28(3)25(23)31/h7-8,11-12,19,21H,4-6,9-10,13-18,20H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...				Bioorg Med Chem Lett 20: 4700-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.143 BindingDB Entry DOI: 10.7270/Q2PR7W6H
					More data for this Ligand-Target Pair