BDBM50322862 (R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210748

SMILES: CN(C)CC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=QLAMXGAMLQKGLG-FQLXRVMXSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322862 ((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...) Show SMILES CN(C)CC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C31H34F3N3O3S/c1-21(20-37(2)3)23-15-16-27-24(17-23)11-7-14-28(27)35-30(38)19-29(22-9-5-4-6-10-22)36-41(39,40)26-13-8-12-25(18-26)31(32,33)34/h4-6,8-10,12-13,15-18,28-29,36H,1,7,11,14,19-20H2,2-3H3,(H,35,38)/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptor				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50322862 ((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...) Show SMILES CN(C)CC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C31H34F3N3O3S/c1-21(20-37(2)3)23-15-16-27-24(17-23)11-7-14-28(27)35-30(38)19-29(22-9-5-4-6-10-22)36-41(39,40)26-13-8-12-25(18-26)31(32,33)34/h4-6,8-10,12-13,15-18,28-29,36H,1,7,11,14,19-20H2,2-3H3,(H,35,38)/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux				Bioorg Med Chem Lett 20: 4593-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.010 BindingDB Entry DOI: 10.7270/Q25Q4W88
					More data for this Ligand-Target Pair