BDBM50322930 1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-N-((R)-1-phenylethyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1209966

SMILES: C[C@@H](NC(=O)N1CCC2(CC1)C(N(C2=O)c1cccc(F)c1)c1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=HOTABMXPOAPWLJ-OEPVSBQMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322930 (1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-N-((R)...) Show SMILES C[C@@H](NC(=O)N1CCC2(CC1)C(N(C2=O)c1cccc(F)c1)c1ccc(Cl)cc1)c1ccccc1 |r| Show InChI InChI=1S/C28H27ClFN3O2/c1-19(20-6-3-2-4-7-20)31-27(35)32-16-14-28(15-17-32)25(21-10-12-22(29)13-11-21)33(26(28)34)24-9-5-8-23(30)18-24/h2-13,18-19,25H,14-17H2,1H3,(H,31,35)/t19-,25?/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair