null

SMILES: C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1cnn(CCN2CCOCC2)c1)c1ccccc1Cl

InChI Key: InChIKey=OENQIJZSDDCZNC-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50323106 ((R)-3-(1-(2-chlorophenyl)ethoxy)-5-(5-(1-(2-morpho...) Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1cnn(CCN2CCOCC2)c1)c1ccccc1Cl |r| Show InChI InChI=1S/C29H29ClN6O3S/c1-19(22-4-2-3-5-23(22)30)39-26-15-27(40-28(26)29(31)37)36-18-32-24-14-20(6-7-25(24)36)21-16-33-35(17-21)9-8-34-10-12-38-13-11-34/h2-7,14-19H,8-13H2,1H3,(H2,31,37)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PLK1 by SPA assay				Bioorg Med Chem Lett 20: 4587-92 (2010) Article DOI: 10.1016/j.bmcl.2010.06.009 BindingDB Entry DOI: 10.7270/Q2MS3SZB
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50323106 ((R)-3-(1-(2-chlorophenyl)ethoxy)-5-(5-(1-(2-morpho...) Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1cnn(CCN2CCOCC2)c1)c1ccccc1Cl |r| Show InChI InChI=1S/C29H29ClN6O3S/c1-19(22-4-2-3-5-23(22)30)39-26-15-27(40-28(26)29(31)37)36-18-32-24-14-20(6-7-25(24)36)21-16-33-35(17-21)9-8-34-10-12-38-13-11-34/h2-7,14-19H,8-13H2,1H3,(H2,31,37)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 using 7-benzyloxyquinoline as substrate by fluorescence plate reader				Bioorg Med Chem Lett 20: 4587-92 (2010) Article DOI: 10.1016/j.bmcl.2010.06.009 BindingDB Entry DOI: 10.7270/Q2MS3SZB
					More data for this Ligand-Target Pair