null

SMILES: C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1ccnc(N)c1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=RXHOSXWWMGMFAO-CQSZACIVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50323108 ((R)-5-(5-(2-aminopyridin-4-yl)-1H-benzo[d]imidazol...) Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1ccnc(N)c1)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C26H20F3N5O2S/c1-14(17-4-2-3-5-18(17)26(27,28)29)36-21-12-23(37-24(21)25(31)35)34-13-33-19-10-15(6-7-20(19)34)16-8-9-32-22(30)11-16/h2-14H,1H3,(H2,30,32)(H2,31,35)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C9 using 7-{3-(4-phenylpiperazin-1-ylmethyl)benzyl}resorufin as substrate by fluorescence plate reader				Bioorg Med Chem Lett 20: 4587-92 (2010) Article DOI: 10.1016/j.bmcl.2010.06.009 BindingDB Entry DOI: 10.7270/Q2MS3SZB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50323108 ((R)-5-(5-(2-aminopyridin-4-yl)-1H-benzo[d]imidazol...) Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1ccnc(N)c1)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C26H20F3N5O2S/c1-14(17-4-2-3-5-18(17)26(27,28)29)36-21-12-23(37-24(21)25(31)35)34-13-33-19-10-15(6-7-20(19)34)16-8-9-32-22(30)11-16/h2-14H,1H3,(H2,30,32)(H2,31,35)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PLK1 by SPA assay				Bioorg Med Chem Lett 20: 4587-92 (2010) Article DOI: 10.1016/j.bmcl.2010.06.009 BindingDB Entry DOI: 10.7270/Q2MS3SZB
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50323108 ((R)-5-(5-(2-aminopyridin-4-yl)-1H-benzo[d]imidazol...) Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2cc(ccc12)-c1ccnc(N)c1)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C26H20F3N5O2S/c1-14(17-4-2-3-5-18(17)26(27,28)29)36-21-12-23(37-24(21)25(31)35)34-13-33-19-10-15(6-7-20(19)34)16-8-9-32-22(30)11-16/h2-14H,1H3,(H2,30,32)(H2,31,35)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 using 7-{3-(4-phenylpiperazin-1-ylmethyl)benzyl}resorufin as substrate by fluorescence plate reader				Bioorg Med Chem Lett 20: 4587-92 (2010) Article DOI: 10.1016/j.bmcl.2010.06.009 BindingDB Entry DOI: 10.7270/Q2MS3SZB
					More data for this Ligand-Target Pair