BDBM50323112 (R)-5-(6-phenyl-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide::CHEMBL1209604

SMILES: C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(cc12)-c1ccccc1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=BFKGTKWTGDQINW-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50323112 ((R)-5-(6-phenyl-1H-benzo[d]imidazol-1-yl)-3-(1-(2-...) Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(cc12)-c1ccccc1)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C27H20F3N3O2S/c1-16(19-9-5-6-10-20(19)27(28,29)30)35-23-14-24(36-25(23)26(31)34)33-15-32-21-12-11-18(13-22(21)33)17-7-3-2-4-8-17/h2-16H,1H3,(H2,31,34)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PLK1 by SPA assay				Bioorg Med Chem Lett 20: 4587-92 (2010) Article DOI: 10.1016/j.bmcl.2010.06.009 BindingDB Entry DOI: 10.7270/Q2MS3SZB
					More data for this Ligand-Target Pair