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SMILES: COc1cccc(NC(=O)c2cc(F)cc(c2)C#N)n1

InChI Key: InChIKey=BSHYRMVWJCNCGV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323302   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50323302
PNG
(3-cyano-5-fluoro-N-(6-methoxypyridin-2-yl)benzamid...)
Show SMILES COc1cccc(NC(=O)c2cc(F)cc(c2)C#N)n1
Show InChI InChI=1S/C14H10FN3O2/c1-20-13-4-2-3-12(17-13)18-14(19)10-5-9(8-16)6-11(15)7-10/h2-7H,1H3,(H,17,18,19)
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PC cid
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Article
PubMed
n/an/a 1.51E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization

Bioorg Med Chem Lett 20: 4390-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.064
BindingDB Entry DOI: 10.7270/Q2V9888D
More data for this
Ligand-Target Pair