BDBM50323317 CHEMBL4175848

SMILES: COc1ccc(cc1)C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1

InChI Key: InChIKey=LSDKEGHHJAOTNT-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50323317 (CHEMBL4175848) Show SMILES COc1ccc(cc1)C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1 Show InChI InChI=1S/C15H12BrN5O2/c1-23-11-5-2-9(3-6-11)15(22)17-13-8-10(16)4-7-12(13)14-18-20-21-19-14/h2-8H,1H3,(H,17,22)(H,18,19,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Desensitization of GPR35 in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution pretreated for 1 hr followed by...				ACS Med Chem Lett 9: 422-427 (2018) Article DOI: 10.1021/acsmedchemlett.7b00510 BindingDB Entry DOI: 10.7270/Q2GB26K8
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50323317 (CHEMBL4175848) Show SMILES COc1ccc(cc1)C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1 Show InChI InChI=1S/C15H12BrN5O2/c1-23-11-5-2-9(3-6-11)15(22)17-13-8-10(16)4-7-12(13)14-18-20-21-19-14/h2-8H,1H3,(H,17,22)(H,18,19,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at GPR35 in human HT-29 cells by dynamic mass redistribution assay				ACS Med Chem Lett 9: 422-427 (2018) Article DOI: 10.1021/acsmedchemlett.7b00510 BindingDB Entry DOI: 10.7270/Q2GB26K8
					More data for this Ligand-Target Pair