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BDBM50323394 5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid::CHEMBL1208923

SMILES: OC(=O)c1n[nH]c2CC(Cc12)c1cc(F)cc(F)c1F

InChI Key: InChIKey=RLMNVSLAEYDKEG-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323394   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50323394
PNG
(5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclop...)
Show SMILES OC(=O)c1n[nH]c2CC(Cc12)c1cc(F)cc(F)c1F
Show InChI InChI=1S/C13H9F3N2O2/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13(19)20/h3-5H,1-2H2,(H,17,18)(H,19,20)
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KEGG

UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]nicotinic acid from human GPR10a receptor


Bioorg Med Chem Lett 20: 4472-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.041
More data for this
Ligand-Target Pair
Hydroxycarboxylic acid receptor 2


(Mus musculus)
BDBM50323394
PNG
(5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclop...)
Show SMILES OC(=O)c1n[nH]c2CC(Cc12)c1cc(F)cc(F)c1F
Show InChI InChI=1S/C13H9F3N2O2/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13(19)20/h3-5H,1-2H2,(H,17,18)(H,19,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]nicotinic acid from mouse GPR10a receptor


Bioorg Med Chem Lett 20: 4472-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.041
More data for this
Ligand-Target Pair