BDBM50323683 CHEMBL1209305::rac-exo-[6-(2-(5-Acetylaminopyridin-3-yl)phenoxy))]-3-azabicyclo[3.2.1]octane hydrochloride

SMILES: CC(=O)Nc1cncc(c1)-c1ccccc1O[C@H]1C[C@H]2C[C@@H]1CNC2

InChI Key: InChIKey=CXOPDJYVJZLVSY-KKVAFCGZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50323683 (CHEMBL1209305 | rac-exo-[6-(2-(5-Acetylaminopyridi...) Show SMILES CC(=O)Nc1cncc(c1)-c1ccccc1O[C@H]1C[C@H]2C[C@@H]1CNC2 |r| Show InChI InChI=1S/C20H23N3O2/c1-13(24)23-17-8-15(10-22-12-17)18-4-2-3-5-19(18)25-20-7-14-6-16(20)11-21-9-14/h2-5,8,10,12,14,16,20-21H,6-7,9,11H2,1H3,(H,23,24)/t14-,16-,20+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>616	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nicotinic receptor expressed in human HEK293 cells				Bioorg Med Chem Lett 20: 4749-52 (2010) Article DOI: 10.1016/j.bmcl.2010.06.142 BindingDB Entry DOI: 10.7270/Q2QC04GV
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human))	BDBM50323683 (CHEMBL1209305 | rac-exo-[6-(2-(5-Acetylaminopyridi...) Show SMILES CC(=O)Nc1cncc(c1)-c1ccccc1O[C@H]1C[C@H]2C[C@@H]1CNC2 |r| Show InChI InChI=1S/C20H23N3O2/c1-13(24)23-17-8-15(10-22-12-17)18-4-2-3-5-19(18)25-20-7-14-6-16(20)11-21-9-14/h2-5,8,10,12,14,16,20-21H,6-7,9,11H2,1H3,(H,23,24)/t14-,16-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha7 nicotinic receptor expressed in human HEK293 cells				Bioorg Med Chem Lett 20: 4749-52 (2010) Article DOI: 10.1016/j.bmcl.2010.06.142 BindingDB Entry DOI: 10.7270/Q2QC04GV
					More data for this Ligand-Target Pair