null
SMILES: CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O
InChI Key: InChIKey=MDTMCHLPEWCDEO-SFTDATJTSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50324028 ((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.118 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membrane | Bioorg Med Chem 18: 6024-30 (2010) Article DOI: 10.1016/j.bmc.2010.06.073 BindingDB Entry DOI: 10.7270/Q2MG7PPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50324028 ((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari Curated by ChEMBL | Assay Description Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation counting | Eur J Med Chem 46: 799-803 (2011) Article DOI: 10.1016/j.ejmech.2010.12.001 BindingDB Entry DOI: 10.7270/Q2CF9R3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50324028 ((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting | Eur J Med Chem 46: 799-803 (2011) Article DOI: 10.1016/j.ejmech.2010.12.001 BindingDB Entry DOI: 10.7270/Q2CF9R3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50324028 ((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membrane | Bioorg Med Chem 18: 6024-30 (2010) Article DOI: 10.1016/j.bmc.2010.06.073 BindingDB Entry DOI: 10.7270/Q2MG7PPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50324028 ((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari Curated by ChEMBL | Assay Description Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting | Eur J Med Chem 46: 799-803 (2011) Article DOI: 10.1016/j.ejmech.2010.12.001 BindingDB Entry DOI: 10.7270/Q2CF9R3C | |||||||||||
More data for this Ligand-Target Pair |