BDBM50324366 3-Phenylsulfonylfuroxan-4-carboxamide::CHEMBL1215574

SMILES: NC(=O)c1no[n+]([O-])c1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=PEFWQSMSSURTDP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50324366 (3-Phenylsulfonylfuroxan-4-carboxamide | CHEMBL1215...) Show SMILES NC(=O)c1no[n+]([O-])c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C9H7N3O5S/c10-8(13)7-9(12(14)17-11-7)18(15,16)6-4-2-1-3-5-6/h1-5H,(H2,10,13)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay				J Med Chem 53: 5467-75 (2010) Article DOI: 10.1021/jm100066y BindingDB Entry DOI: 10.7270/Q2JH3MC8
					More data for this Ligand-Target Pair
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human))	BDBM50324366 (3-Phenylsulfonylfuroxan-4-carboxamide | CHEMBL1215...) Show SMILES NC(=O)c1no[n+]([O-])c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C9H7N3O5S/c10-8(13)7-9(12(14)17-11-7)18(15,16)6-4-2-1-3-5-6/h1-5H,(H2,10,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.58E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Torino Curated by ChEMBL					Assay Description Induction of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay				J Med Chem 53: 5467-75 (2010) Article DOI: 10.1021/jm100066y BindingDB Entry DOI: 10.7270/Q2JH3MC8
					More data for this Ligand-Target Pair