BDBM50324371 4-Hexyloxy-3-phenylsulfonylfuroxan::CHEMBL1215644

SMILES: CCCCCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=PEPVFNXUEUPZBF-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50324371 (4-Hexyloxy-3-phenylsulfonylfuroxan | CHEMBL1215644) Show SMILES CCCCCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H18N2O5S/c1-2-3-4-8-11-20-13-14(16(17)21-15-13)22(18,19)12-9-6-5-7-10-12/h5-7,9-10H,2-4,8,11H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a
Universita degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay				J Med Chem 53: 5467-75 (2010) Article DOI: 10.1021/jm100066y BindingDB Entry DOI: 10.7270/Q2JH3MC8
					More data for this Ligand-Target Pair
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human))	BDBM50324371 (4-Hexyloxy-3-phenylsulfonylfuroxan | CHEMBL1215644) Show SMILES CCCCCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H18N2O5S/c1-2-3-4-8-11-20-13-14(16(17)21-15-13)22(18,19)12-9-6-5-7-10-12/h5-7,9-10H,2-4,8,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Torino Curated by ChEMBL					Assay Description Induction of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay				J Med Chem 53: 5467-75 (2010) Article DOI: 10.1021/jm100066y BindingDB Entry DOI: 10.7270/Q2JH3MC8
					More data for this Ligand-Target Pair