BDBM50324409 (E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-3(4H)-yl)-benzoic Acid::CHEMBL1215441

SMILES: CCCc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1

InChI Key: InChIKey=IDZNQQYUSYPESR-RIYZIHGNSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324409 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-...) Show SMILES CCCc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C26H21N3O5/c1-2-4-17-7-13-23-22(16-17)25(30)28(20-11-9-19(10-12-20)26(31)32)24(27-23)14-8-18-5-3-6-21(15-18)29(33)34/h3,5-16H,2,4H2,1H3,(H,31,32)/b14-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50324409 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-...) Show SMILES CCCc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C26H21N3O5/c1-2-4-17-7-13-23-22(16-17)25(30)28(20-11-9-19(10-12-20)26(31)32)24(27-23)14-8-18-5-3-6-21(15-18)29(33)34/h3,5-16H,2,4H2,1H3,(H,31,32)/b14-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324409 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-...) Show SMILES CCCc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C26H21N3O5/c1-2-4-17-7-13-23-22(16-17)25(30)28(20-11-9-19(10-12-20)26(31)32)24(27-23)14-8-18-5-3-6-21(15-18)29(33)34/h3,5-16H,2,4H2,1H3,(H,31,32)/b14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324409 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-...) Show SMILES CCCc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C26H21N3O5/c1-2-4-17-7-13-23-22(16-17)25(30)28(20-11-9-19(10-12-20)26(31)32)24(27-23)14-8-18-5-3-6-21(15-18)29(33)34/h3,5-16H,2,4H2,1H3,(H,31,32)/b14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair