BDBM50324479 5-amino-4-(3'-hydroxy-[1,1'-biphenyl]-4-ylcarboxamido)-5-oxopentanoic acid::CHEMBL1215443

SMILES: NC(=O)C(CCC(O)=O)NC(=O)c1cccc(c1)-c1cccc(O)c1

InChI Key: InChIKey=CILFKLCFPHNPJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D Synthase (Homo sapiens (Human))	BDBM50324479 (5-amino-4-(3'-hydroxy-[1,1'-biphenyl]-4-ylcarboxam...) Show SMILES NC(=O)C(CCC(O)=O)NC(=O)c1cccc(c1)-c1cccc(O)c1 Show InChI InChI=1S/C18H18N2O5/c19-17(24)15(7-8-16(22)23)20-18(25)13-5-1-3-11(9-13)12-4-2-6-14(21)10-12/h1-6,9-10,15,21H,7-8H2,(H2,19,24)(H,20,25)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay				J Med Chem 53: 5536-48 (2010) Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4
					More data for this Ligand-Target Pair