BDBM50324780 (3R,4R)-N3-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-N4-(1H-indazol-5-yl)-1-(methylsulfonyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1222222

SMILES: CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key: InChIKey=IMNJNDCBMAYSSM-OALUTQOASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324780 ((3R,4R)-N3-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phen...) Show SMILES CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc2[nH]ncc2c1 |r| Show InChI InChI=1S/C25H23FN6O5S/c1-38(36,37)31-13-18(24(34)28-16-5-7-21-15(10-16)12-27-30-21)19(14-31)25(35)29-22-8-6-17(11-20(22)26)32-9-3-2-4-23(32)33/h2-12,18-19H,13-14H2,1H3,(H,27,30)(H,28,34)(H,29,35)/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair