BDBM50324783 (3R,4R)-N3-(4-chlorophenyl)-N4-(4-(2,5-dihydro-1H-pyrrole-1-carbonyl)phenyl)-1-(methylsulfonyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1222225

SMILES: CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1)C(=O)N1CC=CC1)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=UDWQYEIEVDKVQR-SFTDATJTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324783 ((3R,4R)-N3-(4-chlorophenyl)-N4-(4-(2,5-dihydro-1H-...) Show SMILES CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1)C(=O)N1CC=CC1)C(=O)Nc1ccc(Cl)cc1 |r,c:24| Show InChI InChI=1S/C24H25ClN4O5S/c1-35(33,34)29-14-20(21(15-29)23(31)27-19-10-6-17(25)7-11-19)22(30)26-18-8-4-16(5-9-18)24(32)28-12-2-3-13-28/h2-11,20-21H,12-15H2,1H3,(H,26,30)(H,27,31)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair